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EC number: 232-087-8
CAS number: 7785-70-8
a study performed to assess the contact sensitization potential of
turpentine oil by maximization test in humans, panels of 25 healthy
adult male Negroes were induced with five exposures of dermal dose of
50% of turpentine oil in petrolatum for 48 hours using an occlusive
patch followed by challenge dose of 20%. The challenge reaction was read
immediately after removal of the 48 hour patch and again in another two
days. An evident erythema was considered a minimum positive response.
Sensitization potential was rated according to grading system as
described in report,
total of 18 out of 25 subjects showed positive reaction to sensitization
during the study.
the test conditions, turpentine oil was considered to be a strong
sensitizer (Grade 4) in humans.
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