Registration Dossier
Registration Dossier
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EC number: 401-280-0 | CAS number: 91273-04-0 CM 23-376; REOMET 30
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- fish, juvenile growth test
- Adequacy of study:
- supporting study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 215 (Fish, Juvenile Growth Test)
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Endpoint:
- fish early-life stage toxicity
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Referenceopen allclose all
No effects on growth rate and mortility up to the highest test concentration.
Description of key information
Parent substance EC 401 -280 -0
No data on chronic toxicity of the substance EC 401-280-0 are available.
Hydrolysis products
Bis(2 -ethylhexyl)amine
The acute L(E)C50 values for fish and aquatic invertebrates of the most toxic degradation product to aquatic organisms (bis(2-ethylhexyl)amine were determined to be in the same magnitude. A long-term reproduction study with aquatic invertebrates (Daphnia magna) was performed (BASF SE, 2013; report no. 51E0454/11E137) with bis(2-ethylhexyl)amine. Based on the results from this study, the substance is classified as Chronic Category 1. A long-term toxicity study with fish is not available and will not provide any relevant additional information.
1H-1,2,4 -triazole
Supporting data on chronic toxicity of 1H-1,2,4-triazole to fish in a juvenile growth test according to OECD 215 show no effect on growth rate and mortality up to the highest test concentration of 100mg/L. A NOEC of > 100mg/L was determined (ECHA, disseminated REACH Dossier 2014).
formaldehyde
No data from guideline studies on chronic fish toxicity with formaldehyde is available.
As formaldehyde is readily biodegradable, data on chronic toxicity are not considered to be relevant to assess chronic toxicity of the substance EC 401-280- 0 and its hydrolysate.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
