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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: test conducted according to the respective OECD guideline and under GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-difluoro-3-(propane-1-sulfonamido)benzoic acid
EC Number:
700-740-0
Cas Number:
1103234-56-5
Molecular formula:
C10H11F2NO4S
IUPAC Name:
2,6-difluoro-3-(propane-1-sulfonamido)benzoic acid
Details on test material:
-Substance type: organic
-Physical state: white powder
-Storage condition of test material: at room temerature, protected from light

Results and discussion

Water solubility
Water solubility:
> 944 - < 981 g/L
Temp.:
20 °C
pH:
> 2.5 - < 2.8
Details on results:
The initially added amount of test substance was 5 g per litre deionised water. The
measured concentrations were:
944 mg/1 (24 h), 935 mg/1 (48 h) and 981 mg/1 (72 h). The pH values of the solutions
were 2.8, 2.7 and 2.5, respectively.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)
Based on the measured concentrations, the water solubility was determined to be
953 mg/1 at 20 ± 0.5°C and a pH of 2. 7.