Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 606-947-1 | CAS number: 221640-21-7
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- effusion method: by loss of weight or by trapping vaporisate
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: calculated
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Temp.:
- 50 °C
- Vapour pressure:
- 0 Pa
- Temp.:
- 55 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The vapor pressure of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- is calculated as being equal to 2.1 x 10-7 Pa (2.1 x 10E-9 mbar) at 20 °C, and 4.4 x 10E-7 Pa (4.4 x 10E-9 mbar) at 25 °C.
- Executive summary:
The vapor pressure of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was measured using the Knudsen effusion method (mass-loss technique), according to the guidelines OECD 104 / EU A.4. The quality of the apparatus was previously verified with the measurement of well-known reference compounds. Experiments were performed at three temperatures between 70 °C and 90 °C. Results permit the establishment of the relation between the vapor pressure of the compound and temperature, allowing the knowledge of the vapor pressure at different temperatures. Based on the results, the vapor pressure of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- is calculated as being equal to 2.1 x 10-7 Pa (2.1 x 10-9 mbar) at 20 °C, and 4.4 x 10-7 Pa (4.4 x 10-9 mbar) at 25 °C. Therefore 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- is to be considered non volatile in aqueous solution.
Reference
Description of key information
The vapor pressure of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- is calculated as being equal to 0.00000021 (0.0000000021 mbar) at 20 °C, and 0.00000044 Pa (0.0000000044 mbar) at 25 °C.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- is to be considered non volatile in aqueous solution.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
