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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:
Please refer to the category justification provided in the category object.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Alcohols, C12-14 (even-numbered), ethoxylated, magnesium salts, < 2.5 mol EO
EC Number:
939-578-2
Molecular formula:
not applicable
IUPAC Name:
Alcohols, C12-14 (even-numbered), ethoxylated, magnesium salts, < 2.5 mol EO

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
erythema score
Time point:
24/48/72 h
Remarks on result:
other: Irritating based on all available skin irritation data in the Alkyl Ether Sulfates (AES) category.
Irritation parameter:
edema score
Time point:
24/48/72 h
Remarks on result:
other: Irritating based on all available skin irritation data in the Alkyl Ether Sulfates (AES) category.

Any other information on results incl. tables

For a detailed assessment of the skin irritation / corrosion potential of the Alkyl Ether Sulfates (AES) category, please refer to the category justification attached to the category object.

Applicant's summary and conclusion

Interpretation of results:
other: Skin irrit. 2, H315. Classification according to Regulation (EC) No. 1272/2008 (CLP/EU GHS).
Conclusions:
Applying read-across based on grouping of substances (category approach), an irritating potential is predicted for the target substance.
Executive summary:

The available data on skin irritation / corrosion in the Alkyl Ether Sulfates (AES) category indicate a skin irritation potential for the target substance. As explained in the category justification, the differences in molecular structure and composition between the target substance and the members of the AES category are unlikely to lead to differences in the skin irritation / corrosion potential.