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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vitro / ex vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
see attached file
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
ethyl 3-[(pyridin-2-yl)amino]propanoate
EC Number:
600-382-4
Cas Number:
103041-38-9
Molecular formula:
C10 H14 N2 O2
IUPAC Name:
ethyl 3-[(pyridin-2-yl)amino]propanoate

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Basis:
mean
Time point:
other: 240 min
Score:
0
Max. score:
0
Reversibility:
not specified

Applicant's summary and conclusion

Interpretation of results:
slightly irritating
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
Following assessment of the data for all endpoints the test material was considered unlikely to have the potential to cause severe ocular
irritancy in vivo.