Vanadium carbide

Toxicity to other aquatic organisms

Administrative data

Endpoint:

toxicity to other aquatic vertebrates

Type of information:

experimental study

Adequacy of study:

disregarded due to major methodological deficiencies

Reliability:

3 (not reliable)

Rationale for reliability incl. deficiencies:

other: Insufficent information on test methodology (measured/nominal test concentrations are not reported, no phys-chem data measured during the test). No relevant endpoint (LC1 and LC50) for evaluation of chronic effect levels.

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Data source

Reference

Reference Type:

publication

Title:

Aquatic Toxicology of Trace Elements of Coal and Fly Ash.

Author:

Birge W.J.

Year:

1978

Bibliographic source:

Energy and Environmental Stress in Aquatic Systems. Ed. Thorpe, J.H. and Gibbons, J.W., Department of energy Symposium Series. pp 219-240

Materials and methods

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

Semi-static embryo-larval bioassay with the narrow-mouthed toad (Gastrophryne carolensis)

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

Divanadium pentaoxide

EC Number:

215-239-8

EC Name:

Divanadium pentaoxide

Cas Number:

1314-62-1

Molecular formula:

V2O5

IUPAC Name:

divanadium pentaoxide

Details on test material:

No information on test material stated.

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

not specified

Test organisms

Test organisms (species):

Gastrophryne carolinensis

Details on test organisms:

Eggs

Study design

Test type:

semi-static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

7 d

Test conditions

Hardness:

195±5.4 ppm CaCO3

Test temperature:

22.0±1.0°C

pH:

7.4±0.1

Dissolved oxygen:

Dissolved oxygen was maintained near saturation by continuous moderate aeration.

Nominal and measured concentrations:

Measured: 10 to 14 exposure levels.

Details on test conditions:

Eggs were exposed from fertilization through 4 days posthatching, giving treatment periods of 7 days.
Test water and toxicant were renewed at regular 12 hour intervals.
Test organisms were examined daily to tabulate frequencies of mortality and teratogenesis. Control adjusted LC1 and LC50 values were calculated for combined test responses by log probit analysis. Anomalous survivors were counted as lethals.
Control eggs were cultured simultaneously with experimentals and under identical conditions, except for omission of toxic coal elements.
Minimum sample size was set at 150 eggs per culture.
Exposure elements were initiated at 10 to 100 ppm and continued at two- to tenfold dilutions until survival of experimental animals equaled or approached that observed for controls.

Reference substance (positive control):

not specified

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

7 d

Dose descriptor:

LC50

Effect conc.:

230 µg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

element

Remarks:

V

Basis for effect:

other: mortality and teratogenesis

Remarks on result:

other: 95% Cl: 130-410 µg V/L

Effect concentrations 2

Duration:

7 d

Dose descriptor:

other: LC1

Effect conc.:

7.4 µg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

element

Remarks:

V

Basis for effect:

other: mortality and teratogenesis

Remarks on result:

other: 95% Cl: 0.6 - 23 µg V/L