BMS-183981-01

Guidance on Safe Use

First-aid measures

Emergency measure - Inhalation: Remove subject to fresh air.  Give artificial respiration if

breathing has stopped.  Seek immediate medical attention.

Emergency measure - Eyes: Wash with copious amounts of water for 15-20 minutes.  Seek

medical attention.

Emergency measure - Skin: Remove contaminated clothing and wash affected area with

soap and water for at least 15 minutes.  Seek medical

attention if irritation develops or persists.

Emergency measure - Ingestion: Seek medical attention immediately.  Rinse mouth thoroughly

with water if the subject is conscious.  Vomiting may be

induced if person is conscious, is not experiencing

convulsions and if ingestion has occurred within the

previous 3 hours.  Do not induce vomiting if the person is

unconscious.

Fire-fighting measures

Recommended extinguishing agent: Use agents appropriate for surrounding environment.  Water

or foam are suitable.

Product arising from burning: May include CO, CO2 and oxides of nitrogen.

Product determined by test: N

Protective equipment: Full protective clothing, with self contained breathing

apparatus must be worn.

Accidental release measures

Emergency measures in case of spillage: Protective clothing and a respirator must be worn by

operators cleaning up any spillage.

Collect material to minimise dust generation; use wet mop,

damp sponge or wet/dry HEPA vacuum.  Place collected

substance into a suitable container for disposal.  Spill

area should be washed and well ventilated.

Handling and storage

Handling: When engineering controls are not sufficient to control dust

exposure, approved respiratory protection to EN 136 standard

should be worn.  For manufacturing areas, skin protection

should be provided in the form of overalls, or full air

suits along with latex or other impermeable gloves.  Rubber,

neoprene or other gloves may be required if solvents,

corrosives or other chemicals are present.  Chemical safety

glasses should be worn if a full face respirator is not

being worn.

Storage: Store in sealed, upright containers in a dry area away from

heat sources.  Ensure containers are correctly labelled.

Packaging of the substance and or preparation: Fibre drums (47 x 72 cm). 34kg maximum capacity.  UN

approved.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Air transport (UN RTDG/ICAO/IATA)

Shipping

Special provisions / remarks

Remarks:

Transport code: No UN number has been assigned.
Transport: Use normal procedures for transport of industrial chemicals
not considered hazardous for transport. Ensure the
containers are securely held to prevent falling over.

SpecialProvisions

Stability and reactivity

Danger other than fire: None known.

Chemical reaction with water: None known.

Dust explosion: Compound has been tested as a combustible dust with a class

ST-2 explosion strength (ASTM E 1226 Method).  As with any

organic material, a suspended dust cloud of the substance

may ignite if subject to a strong ignition source or static

electricity.  Provide appropriate bonding and grounding to

control static charges.

Dust explosion determined by test: Y

Disposal considerations

Industry - Possibility of recovery/recycling: BMS-183981-01 is consumed in the drug synthesis reaction in

which it is employed.  Significant residue levels in the

reactor effluent are not expected.  No practical means of

recovery or recycling are known.

Industry - Possibility of neutralisation: No method of neutralization is known.

Industry - Possibility of destruction: controlled discharge: Trace quantities are destroyed by biological oxidation in

the wastewater treatment plant prior to discharge to the

sewage system. (A641)

Industry - Possibility of destruction - incineration: Incineration is recommended for larger quantities. A

closed-cycle incinerator with scrubbers should be employed.

National regulations must be observed. (A663)

Industry - Possibility of destruction - water purification: Trace quantities of material in aqueous washes and in other

liquors will be treated in secondary biological waste water

treatment plant before discharge to sewage works.

Industry - Possibility of destruction - other: None

Public at large - Possibility of recovery/recycling: Not applicable.  The material is a chemical intermediate for

the pharmaceutical industry and is not intended for public

use.

Public at large - Possibility of neutralisation: Not applicable

Public at large - Possibility of destruction: controlled discharge: Not applicable

Public at large - Possibility of destruction - incineration: Not applicable

Public at large - Possibility of destruction - water purification: Not applicable

Public at large - Possibility of destruction - others: Not applicable