2-Decyltetradecyl 3-[3-(2-decyltetradecoxy)-3-oxopropyl]sulfanylpropanoate

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

read-across based on grouping of substances (category approach)

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Thiobis Propanoic Acid Derivatives
The category covers thiiodipropionates that are symmetrically esterified by two linear aliphatic groups ranging in size from C10 to C24
The justification for the category is based on the expectation that the close structural similarity should result in properties that are either similar or follow a pattern that correlates with changes in the molecular weights of the compounds. The category members are high-molecular weight dithiopropionate esters that differ only in the chain length of the dialkyl ester functions and are expected to follow a regular pattern for all endpoints.
Based on the structures and molecularweights of the category members, as well as available data on category members, The predictive methods and extrapolation and interpolation of data within the category are acceptable. Data provided by other sources also demonstrate that these compounds generally have mammalian toxicities that are similar (e.g., acute oral LD 50, acute irritation thresholds, and genotoxicities) or follow a pattern that parallels changes in molecular weight (e.g., repeated-dose NOAEL).

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

GLP compliance:

no

Type of method:

effusion method: vapour pressure balance

Key result

Test no.:

#1

Temp.:

20 °C

Vapour pressure:

0.001 Pa

Key result

Test no.:

#2

Temp.:

25 °C

Vapour pressure:

0.001 Pa

Key result

Test no.:

#3

Temp.:

50 °C

Vapour pressure:

0.007 Pa

Conclusions:

The vapour pressure of the test item Propanoic acid, 3,3’-thiobis-, di-C16-22-alkyl esters was calculated by interpolation and extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation EC No. 440/2008 Method A.4. Vapour Pressure and OECD Test Guideline No. 104 (2006) to 5.1 × 10-4 Pa, 8.2 × 10-4 Pa and 7.3 × 10-3 Pa, respectively.

Key value for chemical safety assessment

Vapour pressure:

0.007 Pa

at the temperature of:

20 °C