Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 218-900-9
CAS number: 2277-19-2
A BlueScreen HC Assay was used to determine the genotoxicity of the test
substance. The test is performed on a strain of genetically modified
human lymphoblastoid TK6 cells. The cells are modified for increased
expression of GLuc when exposed to genotoxic chemicals. Coelenterazine
substrate is added to the test media. The coelenterazine reacts with
GLuc, which causes luminescence which can be detected to determine the
amount of GLuc present, and thus the genotoxicity. The test was done
both with and without metabolic activation with S9. The test substance
was not genotoxic with or without metabolic activation. However, the
test substance was cytotoxic.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again