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EC number: 947-836-0
CAS number: -
The hazard assessment of inorganic UVCBs for
the purpose of classification and derivation of fate properties and safe
effect thresholds (e.g. PNEC) is a cumbersome and complex process. Due
to the intrinsic variability of the composition of an UVCB, it is
difficult to select a sample that would unambiguously be representative
for the (eco)toxicological hazard profile of the UVCB and could
subsequently be used for testing. Instead of direct testing, a
precautionary approach is taken where the UVCB is treated as a complex
metal containing substance containing a number of discrete constituents
(metals, metal compounds, non-metal inorganic compounds etc.). For each
of these constituents, the fate and hazard profile is used for deriving
the proper classification of the UVCB (using the mixture rules) and/or
for the derivation of the PNECs and DNELs of the constituent (forwarded
to the risk assessment). Using the fate of all individual constituents
circumvents indirectly the issue of varying composition of an UVCB as it
implicitly assumes that each time the UVCB substance consists of the
pure substance, i.e. that each constituent would be present and
bio-available at a 100% concentration in the UVCB substance. This can be
considered a conservative approach. A main outcome of the constituents’
based assessment is the selection of all the constituents for which any
environmental hazard is identified.
The actual hazard profile and environmental
fate properties of the inorganic UVCB substance and the individual constituents
are dependent on the speciation of each and every constituent and hence
this information needs to be collected and the corresponding information
for the environmental fate properties will be used.
Different scenarios can be encountered.
the speciation of a constituent is known, this is used as such for the
environmental fate properties assessment.
the speciation is unknown or few metal species co-exist, the worst-case
speciation for the purpose of environmental fate assessment and
environmental hazard assessment is selected, i.e. the speciation that
would lead to the most severe effects.
Conclusions on environmental fate properties
are based on available and/or environmental fate worst-case speciation
information for each of the iUVBC constituents. Environmental fate
properties for the iUVCB are assessed by assessing constituents’
transport and distribution, bioaccumulation potential and secondary
poisoning. The other parameters, such as biodegradation or hydrolysis,
are not applicable or relevant for inorganic constituents.
The iUVCB classification is calculated by
applying the CLP mixture rules based on the classification of the known
or worst-case speciation for each constituent and worst-case constituent
concentration in the iUVCB (i.e. maximum of the legal entity typical
value), using the MeClas tool. Depending on the availability of
information, the iUVCB classification can be refined following the
MeClas Tiered approach.
The assessment of "Germanium
hydroxide oxides, amorphous silica and sodium chloride, recovery
products from germanium refining"
is only based on
the Ge constituent (GeO2), because all other contituents do
not add to the hazard properties of this UVCB (see classification and
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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