Tosylchloramide sodium

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

09 March 2007 - 27 March 2007

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study performed under GLP and according to OECD guidelines.

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

GLP compliance:

yes (incl. QA statement)

Type of method:

other: Differential scanning calorimetry (DSC) and Capillary Tube in a Metal Block

Key result

Decomposition:

yes

Decomp. temp.:

>= 120 - <= 165 °C

Thermal Stability (DSC)

The DSC-measurement in the closed glass crucible showed an endothermic effect in the temperature range 65 - 90 ºC and an exothermal decomposition in the temperature range 120 - 150 ºC.

Melting Point 1 Melting Ranqe (DSC)

The DSC-measurements in aluminium crucibles with a hole showed three endothermic effects (dehydration) in the temperature ranges 70 -90ºC, 105 -135°C and 135 -155ºC and an exothermal decomposition in the temperature range 155 - 165ºC with an energy of 120 J/g. After the DSC-measurement the test item was not melt, it still remained a solid. Three additional measurements with the capillary method were performed to clarify the results of the DSC measurements.

No	set point	heating rate	end point	melting point	remarks
1	60 ºC	2K/min	170ºC	-	The test item started to sinter at 80 ºC,133 ºC appearance of gas bubbles,138 ºC arise of the sample,141 ºC sample was arisen out of sight,145 ºC test abortedNo melting was observed over the measurment
2	100ºC	3K/min	180ºC	-	90 ºC test item sintered,123 ºC appearance of gas bubbles, arise of the sample136 ºC higher rate of gas bubbles,140 ºC tube empty, sample evaporated141 ºC test abortedNo melting was observed over the measurement
3	140ºC	5K/min	180ºC	-	approx. 100 ºC test item sintered,135 -145 ºC appearance of gas bubbles, arise of thesample150 "C tube empty, sample evaporated153 "C test abortedNo melting was observed over the measurement

According to the results of both methods it can be stated that the test item has no melting point. The endothermic effects observed in the DSC-measurements correspond to physical transformations of the test item e.g. to changes in the crystalline structure due to a stepwise dehydration of the test item (tri hydrate). The test item decomposes first at approximately 120ºC-165ºC.

Conclusions:

Substance has no melting point at atmospheric pressure. It decomposes first at approximately 120-165 ºC.

Executive summary:

A study was performed under GLP and according to OECD102 using Differential Scanning Calorimetry (DCS) and capillary method (metal block) methods to determine the melting point for Tosylchloramide sodium. Substance has no melting point at atmospheric pressure. It decomposes first at approximately 120-165 ºC.

Description of key information

Tosylchloramide sodium has no melting point at atmospheric pressure and decomposes at temperatures of 120 - 165ºC. The internal database of EpiSuite also mentions a 170 °C melting point. To conduct the CSA, the higher decomposition temperature will thus be stated as the melting point temperature.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

165 °C