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EC number: 257-913-4
CAS number: 52434-90-9
Log BCF (regression-based estimate): 2.31 (BCF = 202 L/kg wet-wt)Biotransformation Half-Life (days) : 1.87e-005 (normalized to 10 g fish)Log BAF (Arnot-Gobas upper trophic): 1.10 (BAF = 12.5 L/kg wet-wt)
Log BCF (regression-based estimate):
Log Kow used by BCF estimates: 4.00 (user entered)
Equation Used to Make BCF estimate: Log BCF = 0.6598 log Kow - 0.333 + Correction
Correction(s): ValueNo Applicable Correction Factors
Estimated Log BCF = 2.306 (BCF = 202.4 L/kg wet-wt)
Whole Body Primary Biotransformation Rate Estimate for Fish:
LOG BIOTRANSFORMATION FRAGMENT DESCRIPTION
Aliphatic bromide [-Br]
Log Kow = 4.00 (user-entered)
Molecular Weight Parameter
LOG Bio Half-Life (days)
Bio Half-Life (days)
Bio Half-Life Normalized to 10 g fish at 15 deg C
Biotransformation Rate Constant:
kM (Rate Constant): 25 /day (10 gram fish) **kM (Rate Constant): 14.06 /day (100 gram fish) **kM (Rate Constant): 7.906 /day (1 kg fish) **kM (Rate Constant): 4.446 /day (10 kg fish) **** Predicted value exceeds theoretical whole body maximum value.kM (Rate Constant) of 25 /day is recommended/applied for 10 g fish
Arnot-Gobas BCF & BAF Methods (including biotransformation rate estimates):Estimated Log BCF (upper trophic) = 1.096 (BCF = 12.49 L/kg wet-wt)Estimated Log BAF (upper trophic) = 1.096 (BAF = 12.49 L/kg wet-wt)Estimated Log BCF (mid trophic) = 1.222 (BCF = 16.67 L/kg wet-wt)Estimated Log BAF (mid trophic) = 1.222 (BAF = 16.67 L/kg wet-wt)Estimated Log BCF (lower trophic) = 1.260 (BCF = 18.18 L/kg wet-wt)Estimated Log BAF (lower trophic) = 1.262 (BAF = 18.27 L/kg wet-wt)
Arnot-Gobas BCF & BAF Methods (assuming a biotransformation rate of zero):Estimated Log BCF (upper trophic) = 3.015 (BCF = 1034 L/kg wet-wt)Estimated Log BAF (upper trophic) = 3.373 (BAF = 2360 L/kg wet-wt)
The bioaccumulation potential of substance AP 729 has been predicted using the EPI-Suite (v4.11) BCFBAF v3.01 models and gave the following results:
BCF = 202 L/kg wet-wt (Log BCF = 2.31, regression-based estimate)BAF = 12.5 L/kg wet-wt (Log BAF = 1.10, Arnot-Gobas upper trophic) Biotransformation Half-Life (days) = 1.87e-005 (normalized to 10 g fish)
It is therefore concluded that the potential for bioaccumulation of the substance is low and biotrasformation is very fast.
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