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EC number: 257-913-4
CAS number: 52434-90-9
The partition coefficient of test item AP 729 was determined in the present study according to OECD Test Guideline 117 (HPLC method).
The dead time t0 was determined by using Thiourea as unretained substance.Six reference standards of known log Pow and the test item were analyzed by HPLC: the retention times were determined and the capacity factors ‘k’ were calculated.The partition coefficient of the test item AP 729 was obtained by interpolation of the calculated capacity factor ‘k’ on the calibration graph of ‘log k’ versus ‘log Pow’ for the reference substances with appropriate ‘log Pow’ values.The partition coefficient (log Pow)of AP 729 was found to be 4.31 for Replication 1 and 4.31 for Replication 2.
The mean partition coefficient of AP 729 (log Pow) was 4.31 at 30°C.
The partition coefficient of test item AP 729 was determined according to OECD Test Guideline 117 (HPLC method).
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