Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 220-246-4 | CAS number: 2687-12-9
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- no data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- No study report available for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 997
Materials and methods
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- inhalation
Results and discussion
Effect levels
- Key result
- Dose descriptor:
- LC50
- Effect level:
- 29 mg/m³ air
- Based on:
- not specified
- Exp. duration:
- 4 h
- Clinical signs:
- other: see other findings
- Other findings:
- Behavioral: somnolence (general depressed activity)
Lungs, Thorax, or Respiration: Respiratory depression
Nutritional and Gross Metabolic: body temperature decrease
Autonomic Nervous System: smooth muscle relaxant (mechanism undefined, spasmolytic)
Immunological Including Allergic - increase in cellular immune response
Sense Organs and Special Senses (Eye): lacrimation, conjunctive irritation, corneal damage
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
