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EC number: 203-016-8
CAS number: 102-24-9
TMBX is hydrolytically unstable and breaks
down to form methanol and boric acid in the presence of water, these
species can be expected to be found following release to the
environment. Therefore, an assessment of ecotoxicological potential was
conducted taking account of the effects of the hydrolysis breakdown
products of TMBX upon the different trophic levels.
Testing of Respiration inhibition of Activated sludge by methanol was
conducted by Klecka et al 1985. The IC50 was in excess of 1000 mg/L
based on nominal test material concentrations.
Taking into account the extensive information on the toxicity of boron
to microorganism in STP, i. e. - 4 respiration studies using activated
sludge, showing NOEC between 17.5 and >10000 mg B/L, - 1 nitrification
study in a fixed bed reactor, showing no effect up to 500 mg B/L, and -
3 studies of growth of protozoans relevant for the functioning of STPs,
show NOEC data between 10 and 20 mg B/L. Therefore, it
was decided to base the PNECstp on the lowest NOEC from the available
toxicity data. The lowest NOEC for the protozoan Opercularia bimarginata
on growth is 10 mg B/L (Guhl. 2000). Since the studies of STP
functioning showed no adverse effects at higher concentrations, no
additional assessment factor was used, therefore resulting in e PNECstp
of 10 mg B/L.
Based on the above results, the NOEC value for boron were used to
calculate equivalent values for TMBX:
Respiration inhibition NOEC=10 x (173.5/32.4) = 53.5 mg/L
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