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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
31 October 2017 to 19 December 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: isothermal thermogravimetry
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Sponsor and 10037-115-5
- Expiration date of the lot/batch: 06 June 2019
- Purity test date: 06 June 2017
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
1 Pa
Key result
Test no.:
#2
Temp.:
20 °C
Vapour pressure:
0.008 mm Hg
Key result
Test no.:
#3
Temp.:
25 °C
Vapour pressure:
1.8 Pa
Key result
Test no.:
#4
Temp.:
25 °C
Vapour pressure:
0.013 mm Hg

See attached for detailed results of isothermal TGA analysis

Conclusions:
The isothermal TGA effusion method was applied for the determination of the vapour pressure of Trimethoxyboroxine (TMBX).
The vapour pressure of the test item was: 1.0 Pa (7.6E-3 mmHg) at 20°C (293K) and 1.8 Pa (1.3E-2 mmHg) at 25°C (298K).

Description of key information

The isothermal TGA effusion method was applied for the determination of the vapour pressure of Trimethoxyboroxine (TMBX).

The vapour pressure of the test item was:  1.0 Pa (7.6E-3 mmHg)   at 20°C (293K) and 1.8 Pa (1.3E-2 mmHg) at  25°C (298K).

Key value for chemical safety assessment

Vapour pressure:
1 Pa
at the temperature of:
20 °C

Additional information