Registration Dossier
Registration Dossier
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EC number: 200-720-7 | CAS number: 69-93-2
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- About 10 g of test material was mixed in 100 ml water and then it was temperated to 20 OC. After 1 hour, the mixing was stopped and some ml sample was taken through a filter. The sample was placed into the spectrofotometer and the absorbance was measured. from the calibration line, or from the correlation equation the concentra-tion of uric acid can be calculated. (Result: Absorbance: 1,232 Concentration: 1,476 mg/100 ml)
- GLP compliance:
- no
- Type of method:
- other: UV-Vis spectrofotometer: Simadzu UV1800
- Remarks:
- Cuvette: OPTECH S/Q/10 quarz, 10*10 mm
Test material
- Reference substance name:
- Uric acid
- EC Number:
- 200-720-7
- EC Name:
- Uric acid
- Cas Number:
- 69-93-2
- Molecular formula:
- C5H4N4O3
- IUPAC Name:
- 7,9-dihydro-1H-purine-2,6,8(3H)-trione
- Test material form:
- solid: particulate/powder
- Details on test material:
- It was manufactured by MOLAR CHEMICALS Ltd.
1
Results and discussion
Water solubility
- Key result
- Water solubility:
- ca. 15.52 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 100 g/L
- Incubation duration:
- ca. 1 h
- Temp.:
- 20 °C
- pH:
- ca. 4.976
Applicant's summary and conclusion
- Conclusions:
- solubility in water is 15.52 mg/l
- Executive summary:
solubility in water is 15.52 mg/l
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