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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09 - 28 Nov 1988
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
yes
Analytical monitoring:
no
Vehicle:
no
Details on test solutions:
Direct weighing and mixing with test water (stock solution 100 mg/L): test concentrations by dilution with test medium
Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)
Details on test organisms:
Origin: West-Aquarium, Bad Lauterberg, Germany
Age at study initiation: ca. 4 months
Length (range): 25 - 35 mm at study initiation
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Test temperature:
22°C
Nominal and measured concentrations:
6.3, 8.8, 12.5, 17.7, 25.0 mg/L
Reference substance (positive control):
not specified
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
7.2 mg/L
Nominal / measured:
nominal
Conc. based on:
act. ingr.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
12.5 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
The LC50 was calculated as geometric mean value of LC0 (6.3 mg/L) and LC100 (25 mg/L)
Validity criteria fulfilled:
yes
Conclusions:
The 96-h LC50 to Danio rerio was calculated at 12.5 mg/L corresponding to 7.2 mg/L act. ingr. The substance is considered to be acutely toxic to fish.

Description of key information

The substance has a 96-h LC50 of 12.5 mg/L corresponding to 7.2 mg/L act. ingr. The substance is considered to be acutely toxic to fish.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
7.2 mg/L

Additional information