Registration Dossier
Registration Dossier
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EC number: 292-324-6 | CAS number: 90604-31-2
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Data from secondary source
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Acute dermal toxicity for CAS no: 90604-31-2
- Author:
- EUROPEAN COMMISSION – European Chemicals Bureau
- Year:
- 2 000
- Bibliographic source:
- IUCLID DATASET, 2000
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- Principles of method if other than guideline:
- Acute dermal toxicity study of Alcohols, C13-15 was performed in rabbits.
- GLP compliance:
- not specified
- Test type:
- other: not specified
- Limit test:
- no
Test material
- Reference substance name:
- Alcohols, C13-15
- EC Number:
- 292-324-6
- EC Name:
- Alcohols, C13-15
- Cas Number:
- 90604-31-2
- Molecular formula:
- C15H32O
- IUPAC Name:
- Alcohols, C13-15
- Test material form:
- liquid
- Details on test material:
- - Name of test material: Alcohols, C13-15
- IUPAC name: Alcohols, C13-15
- Molecular formula:C13H280 + C15H32O
- Molecular weight: 208.78 g/mole
- Substance type: Organic
- Physical state: Liquid
- SMILES:CCCCCCCCCCCCCO
Constituent 1
- Specific details on test material used for the study:
- - Name of test material: Alcohols, C13-15
- IUPAC name: Alcohols, C13-15
- Molecular formula:C13H280 + C15H32O
- Molecular weight: 208.78 g/mole
- Substance type: Organic
- Physical state: Liquid
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No data available
Administration / exposure
- Type of coverage:
- other: dermal
- Vehicle:
- not specified
- Details on dermal exposure:
- No data available
- Duration of exposure:
- No data available
- Doses:
- 2000
- No. of animals per sex per dose:
- No data available
- Control animals:
- not specified
- Details on study design:
- No data available
- Statistics:
- No data available
Results and discussion
- Preliminary study:
- No data available
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: No mortality observed
- Mortality:
- No mortality observed
- Clinical signs:
- other: No data available
- Gross pathology:
- No data available
- Other findings:
- No data available
Applicant's summary and conclusion
- Interpretation of results:
- other: Not classified
- Conclusions:
- The LD50 value was considered to be >2000mg/kg bw. When rabbits were treated with Alcohols, C13-15 (90604-31-2) by dermal application.
- Executive summary:
Acute dermal toxicity study was carried out in rabbits using Alcohols, C13-15(90604-31-2).No mortality was observed at dose 2000 mg/kg bw. HenceThe LD50 value was considered to be >2000mg/kg bw. When rabbits were treated withAlcohols, C13-15(90604-31-2) by dermal application.
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