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EC number: 292-324-6 | CAS number: 90604-31-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data is from OECD QSAR toolbox version.3.3 and QMRF report has been attached.
- Qualifier:
- according to guideline
- Guideline:
- other: Predicted data
- Principles of method if other than guideline:
- Prediction is done using QSAR Toolbox version 3.3 with log kow as the primary discriptors.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material: Alcohols, C13-15
- IUPAC name: Alcohols, C13-15
- Molecular formula:C13H280 + C15H32O
- Molecular weight: 208.78 g/mole
- Substance type: Organic
- Physical state: Liquid - Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 369.843 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: not toxic
- Conclusions:
- Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the closest read across substances, the toxicity to aquatic invertebrate was predicted Alcohols, C13-15 (CAS: 90604-31-2). EC50 Intoxication value was estimated to be 369.843 mg/l for Daphnia magna for 48 hrs duration. It was concluded that Alcohols, C13-15 (CAS: 90604-31-2) was likely to be not toxic to aquatic invertebrate.
- Executive summary:
Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the closest read across substances, the toxicity to aquatic invertebrate was predicted Alcohols, C13-15 (CAS: 90604-31-2). EC50 Intoxication value was estimated to be 369.843 mg/l for Daphnia magna for 48 hrs duration. It was concluded that Alcohols, C13-15 (CAS: 90604-31-2) was likely to be not toxic to aquatic invertebrate.
Reference
The
prediction was based on dataset comprised from the following
descriptors: EC50
Estimation method: Takes average value from the 5 nearest neighbours
Domain logical expression:Result: In Domain
((((((((("a"
or "b" )
and "c" )
and "d" )
and ("e"
and (
not "f")
)
)
and ("g"
and (
not "h")
)
)
and ("i"
and (
not "j")
)
)
and ("k"
and (
not "l")
)
)
and ("m"
and (
not "n")
)
)
and ("o"
and "p" )
)
Domain
logical expression index: "a"
Referential
boundary: The
target chemical should be classified as Long chain alcohols by OECD HPV
Chemical Categories
Domain
logical expression index: "b"
Referential
boundary: The
target chemical should be classified as Class 1 (narcosis or baseline
toxicity) by Acute aquatic toxicity classification by Verhaar (Modified)
Domain
logical expression index: "c"
Referential
boundary: The
target chemical should be classified as Biodegrades Fast by Biodeg
probability (Biowin 7) ONLY
Domain
logical expression index: "d"
Referential
boundary: The
target chemical should be classified as days - weeks by Biodeg primary
(Biowin 4) ONLY
Domain
logical expression index: "e"
Referential
boundary: The
target chemical should be classified as Neutral Organics by US-EPA New
Chemical Categories
Domain
logical expression index: "f"
Referential
boundary: The
target chemical should be classified as Aliphatic Amines OR Anionic
Surfactants OR Ethylene Glycol Ethers OR Nonionic Surfactants OR Not
categorized by US-EPA New Chemical Categories
Domain
logical expression index: "g"
Referential
boundary: The
target chemical should be classified as (N/A) by Database Affiliation
Domain
logical expression index: "h"
Referential
boundary: The
target chemical should be classified as Aquatic Japan MoE by Database
Affiliation
Domain
logical expression index: "i"
Referential
boundary: The
target chemical should be classified as (N/A) by Database Affiliation
Domain
logical expression index: "j"
Referential
boundary: The
target chemical should be classified as Eye Irritation ECETOC by
Database Affiliation
Domain
logical expression index: "k"
Referential
boundary: The
target chemical should be classified as Aliphatic alcohol [-OH] AND
-CH2- [linear] AND Linear C4 terminal chain [CCC-CH3] AND Methyl
[-CH3] by Bioaccumulation - metabolism alerts
Domain
logical expression index: "l"
Referential
boundary: The
target chemical should be classified as Aromatic fluoride [-F] by
Bioaccumulation - metabolism alerts
Domain
logical expression index: "m"
Referential
boundary: The
target chemical should be classified as Aliphatic alcohol [-OH] AND
-CH2- [linear] AND Linear C4 terminal chain [CCC-CH3] AND Methyl
[-CH3] by Bioaccumulation - metabolism alerts
Domain
logical expression index: "n"
Referential
boundary: The
target chemical should be classified as -CH- [linear] by
Bioaccumulation - metabolism alerts
Domain
logical expression index: "o"
Parametric
boundary:The
target chemical should have a value of log Kow which is >= 0.345
Domain
logical expression index: "p"
Parametric
boundary:The
target chemical should have a value of log Kow which is <= 5.76
Description of key information
Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the closest read across substances, the toxicity to aquatic invertebrate was predicted Alcohols, C13-15 (CAS: 90604-31-2). EC50 Intoxication value was estimated to be 369.843 mg/l for Daphnia magna for 48 hrs duration. It was concluded that Alcohols, C13-15 (CAS: 90604-31-2) was likely to be not toxic to aquatic invertebrate.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 369.843 mg/L
Additional information
Following studies of target chemical and structurally similar read across includes predicted data and experimental data to conclude the toxicity extent of Alcohols, C13-15 (CAS: 90604-31-2) towards aquatic invertebrate is summarized as follows:
Based on the prediction done using the OECD QSAR toolbox version 3.3 with log kow as the primary descriptor and considering the closest read across substances, the toxicity to aquatic invertebrate was predicted Alcohols, C13-15 (CAS: 90604-31-2). EC50 Intoxication value was estimated to be 369.843 mg/l for Daphnia magna for 48 hrs duration. It was concluded that Alcohols, C13-15 (CAS: 90604-31-2) was likely to be not toxic to aquatic invertebrate.
The above predicted data of target chemical is supported by the experimental study of structurally similar read across Heptan-1-ol (CAS: 111-70-6) from the publication Aquatic Toxicology 1983, suggests that the Short term toxicity test was carried out of Heptan-1-ol on aquatic invertebrate to stuidy the effects.
Lethal concentration to 50% of Hydra oligactis LC50 value of the Heptan-1-ol was found to be 160 mg/L. It can be concluded fromthe value that the Heptan-1-ol is not toxic to the aquatic invertebrate and can be considered as "not classified" as per the classification criteria for aquatic environment.
Another supporting experimental study for the structurally similar read across Pentan-1-ol (CAS: 71-41-0) from the publication Zeitschrift für Wasser und Abwasserforschung 1982, also suggests that the Short term toxicity test was carried out to study the effects of Pentan-1-ol on aquatic invertebrate.
Effective concentration to 50% of Daphnia magna when exposed to Pentan-1-ol for 24 h is 423 mg/L. It can be concluded from the value that the Pentan-1-ol is not toxic to the aquatic invertebrateand can be considered as “not classified” as per the classification criteria for aquatic environment.
Thus based on the effect concentrations which is in the range 160 mg/L to423 mg/lgive the conclusion that test substance Alcohols, C13-15 (CAS: 90604-31-2)is likely to be not toxic to aquatic environment at environmentally relevant concentrations and applying weight of evidence approach it can be considered to be “not classified” as per the CLP classification criteria.
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