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EC number: 238-523-3
CAS number: 14516-71-3
In an acute dermal toxicity study (17-459) groups of Wistar rats (5/sex)
were dermally exposed (semi-occlusive) to UV-1084 (99.1%) for 24 hours.
Animals were then observed for 14 days.
Dermal LD50 (Males/Females) = >2000 mg/kg bw
The test substance applied at a dose of 2000 mg/kg of body weight did
not cause death of any animals. There were no effects on body weight
throughout the study. No clinical signs of toxicity were observed during
the entire study. No macroscopic changes were diagnosed during
This acute dermal study is classified as acceptable. It does satisfy the
guideline requirement for an acute oral study (OECD 402) in the rat.
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