Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vivo

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

2,2'(Octadec-9-enylimino)bisethanol CAS NO 25307-17-9 was tested in a bacterial reverse mutation assay () and was not mutagenic with or without S9 mix. It was also tested for mammalian cell gene mutation in the L5178Y TK +/- Mouse lymphoma assay and was not mutagenic. In addition it was tested in a Chromosomal aberration test in human lymphocytes in-vitro and was found to be not clastogenic. All tests were to current OECD/EU protocols carried out to GLP and with a clearly defined and described test substance. Based on this it can be concluded that 2,2'(Octadec-9-enylimino)bisethanol CAS NO 25307-17-9 would not be expected to have any genotoxic hazard to human health.

Short description of key information:

2,2'(Octadec-9-enylimino)bisethanol CAS NO 25307-17-9 was tested in three in-vitro genotoxicty studies to current protocol and carried out to GLP with well defined test substance.  All three test were negative.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Based on the three negative in-vitro tests for genotoxicity of the read across substance 2,2'(Octadec-9-enylimino)bisethanol CAS NO 25307-17-9 does not require classification as a mutagen according to the European Union CLP/GHS criteria.