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EC number: 946-670-6
CAS number: -
The skin corrosion potential of Cedarwood Virginia oil was
tested according to OECDTG431. A human three dimensional
epidermal model (EpiDerm) was exposed topically to 50µL
undiluted Cedarwood Virginia oil, Milli-Q (negative
control), or Potassium hydroxide (positive control) for 3
minutes, or 1 hour. Skin corrosion is expressed as the
remaining cell viability after exposure to the test
item. The relative mean tissue viability obtained after
3-minute and 1-hour treatments with the test item compared
to the negative control tissues was 94% and 103%,
respectively. Both the negative and the positive control
were considered valid. The mean relative tissue viability
for Cedarwood Virginia oil was above 50% after the 3-minute
treatment and above 15% after the 1-hour treatment. Based
these results, the test substance does not need to be
classified for skin corrosion in accordance with the
criteria outlined in Annex I of the CLP Regulation
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