Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation, other
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:
The target substance is included in a category where a trend is identified. Data for the substance that follows the target indicate skin sensitization properties, therefore, the substance is skin sensitizer for extrapolation. See Category rationale for further details.

Data source

Materials and methods

Test material

1
Reference substance name:
Lubricating oils, used, distd.
EC Number:
295-421-1
EC Name:
Lubricating oils, used, distd.
Cas Number:
92045-40-4
IUPAC Name:
Lubricating oils, used, distd.
Test material form:
liquid

Results and discussion

In vivo (LLNA)

Results
Key result
Parameter:
other: Read-across basing on grouping of substances (category approach)
Remarks on result:
other: Based on the read- across approach (category approach), the substance can be considered skin sensitizer.

Applicant's summary and conclusion

Interpretation of results:
Category 1 (skin sensitising) based on GHS criteria
Conclusions:
Based on the read- across approach (category approach), the substance can be considered skin sensitizer.