Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-800-2
CAS number: 9025-57-4
The aquatic toxicity data for xylananse were obtained from short
term toxicity studies in species representing three trophic levels (i.e.
algae, crustaceans and fish). Xylanase was not toxic to aquatic
organisms and the derived NOEC of 22.2 mg aep/L was used for PNEC
derivation and the assessment factors 1000 and 10000 were applied for
fresh and marine water, respectively.
The PNEC value for STP (sewage treatment plants)is based on actual
measurements of enzyme concentration in STP connected to manufacturing
site. Up to 65000 µg active enzyme protein were detected in STP
connected to manufacturing site and since there was no negative impact
observed, this concentration is the estimated PNEC value for STP.
PNEC values for sediment exposure have not been derived because
xylanase is readily biodegradable, highly water soluble and has a very
low potential for adsorption to sediments. Exposure of the sediment to
toxicologically significant concentrations of the test substance is thus
As no soil ecotoxicity data are available for alpha-amylase, the
PNEC for soil is based on the PNEC for surface water using the
equilibrium partitioning method. PNEC soil was estimated to 2.61*10
-3mg aep/kg soil ww (wet weight) and PNEC for soil dry weight (dw)
to 2.95*10-3 mg aep/kg soil dw.
Xylanase is not expected to cause any significant secondary
poisoning as it is ready biodegradable and has no bioaccumulation
potential. Furthermore, as xylanase is a protein it is expected to be
degraded in the gastrointestinal tract. Thus PNEC oral is not relevant.
Based on the aquatic toxicity studies and the ready biodegradation of
the enzyme, xylanase is not classified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again