Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 277-616-3
CAS number: 73816-74-7
Reactive Red 45:1,was
tested for the evaluation the
potential ocular corrosivity or severe irritancy as measured by its
ability to induce opacity and increased permeability in an isolated
The test was performed
according to the OECD Test Guideline No. 437, Bovine Corneal Opacity and
Permeability Test Method for Identifying i) Chemicals Inducing Serious
Eye Damage and ii) Chemicals Not Requiring Classification for Eye
Irritation or Serious Eye Damage, Adopted 26thJuly 2013.
The test was performed using
nine isolated bovine corneas. The testing was performed on three groups
of corneas: test substance treatment group, positive control group and
negative control group. Three corneas per group were used.
method was used, because the test substance was applicable by
micropipette. The opacity and permeability of each cornea were measured.The
In Vitro Irritancy Score (IVIS) was calculated from the values of
opacity and permeability.
The In Vitro Irritancy Score
(IVIS) for Reactive Red 45:1 was 31.51. This result could be affected by
higher opacity values (colouring of corneas after removing the test
On the basis of score (IVIS)
given above the classification according to the criteria of the UN GHS
could not be performed.
No prediction can be made on
test substance potential to cause eye irritation or serious eye damage.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Sellel veebilehel kasutatakse küpsiseid, et tagada lehe parim kasutus.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again