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EC number: 214-881-6
CAS number: 1205-17-0
Table 1: Summary of Scores for the First Batch of Test
601 (right eye)
602 (left eye)
603 (right eye)
Table 2: Summary of Scores for the Second Batch of
611 (right eye)
612 (left eye)
613 (right eye)
Table 3: Summary of Scores for the Third Batch of Test
621 (right eye)
622 (left eye)
623 (right eye)
A study was conducted to assess the potential of the test material to
cause irritation to the eyes of rabbits using methodology similar to
that outlined in the standardised guideline OECD 405.
The eye irritation potential of three batches of the test material was
assessed in male JW rabbits (three per batch). The dose level
administered was 0.1 mL/eye. The eyes of the rabbits were closed for
about one second after instillation. Observations were made at 1 hour
after instillation and then every 24 hours for a total duration of 72
hours. The Draize scoring system was used to determine the degree of eye
At the 24, 48 and 72 hour time points, no eye in any rabbit showed any
reaction to the test material with regard to the cornea, iris, redness,
chemosis and discharge. All scores were 0.
Under the conditions this study, the test material is not classified as
an ocular irritant in accordance with EU criteria.
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