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EC number: 241-727-5
CAS number: 17736-08-2
Readily biodegradable: 85.2% in 28 d (OECD 301 B); read-across
There is no study available investigating the ready
biodegradability of (Z)-N-methyl-N-(1-oxo-9-octadecenyl)glycine,
compound with 2,2',2''-nitrilotri(ethanol) (1:1) (CAS 17736-08-2). In
accordance with Regulation (EC) No 1907/2006 Annex XI, 1.5 a read-across
to the structurally related source substance
(Z)-N-methyl-N-(1-oxo-9-octadecenyl)glycine (CAS 110-25-8) was
conducted. This read-across is justified in detail within the analogue
justification in IUCLID Section 13.
The study with the read-across substance
(Z)-N-methyl-N-(1-oxo-9-octadecenyl)glycine (CAS 110-25-8) was conducted
according to the OECD guideline 301B using non-adapted activated sludge
from a municipal waste water treatment plant. In this CO2 evolution
test, 20 mg/L source substance (based on TOC) was inoculated with 25
mg/L activated sludge for 28 d under aerobic conditions and aeration
with CO2-free air. Inoculum blanks, an abiotic sterile control and a
toxicity control were run in parallel. CO2 was trapped in bottles
containing 0.25 M NaOH solution and the evolution of CO2 concentration
was followed by TOC analysis in regular intervals. After 28 d
incubation, the test item was degraded by 85.2% in terms of CO2
Based on the available results from a structurally related
read-across substance (in accordance with Regulation (EC) No 1907/2006
Annex XI, 1.5) which is characterized by a similar ecotoxicological
profile and comparable structure, it is concluded that
(Z)-N-methyl-N-(1-oxo-9-octadecenyl)glycine, compound with
2,2',2''-nitrilotri(ethanol) (1:1) (CAS 17736-08-2) can be expected to
be readily biodegradable according to the OECD guideline criteria.
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