Registration Dossier
Registration Dossier
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EC number: 200-929-3 | CAS number: 76-05-1
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was performed in compliance with the GLP. The purpose of this acute inhalation study was focussed on the determination of the irritant potential of TFA on the upper respiratory tract in rat rather than the determination of the LC50 value.
Data source
Reference
- Reference Type:
- other: ECHA disseminated dossier
- Title:
- No information
- Report date:
- 2014
Materials and methods
- Limit test:
- no
Test material
- Reference substance name:
- Trifluoroacetic acid
- EC Number:
- 200-929-3
- EC Name:
- Trifluoroacetic acid
- Cas Number:
- 76-05-1
- Molecular formula:
- C2HF3O2
- IUPAC Name:
- trifluoroacetic acid
Constituent 1
Administration / exposure
- Duration of exposure:
- h
Results and discussion
Effect levelsopen allclose all
- Sex:
- male
- Dose descriptor:
- other: NOAEC
- Effect level:
- ca. 300 mg/m³ air (nominal)
- Based on:
- test mat.
- Exp. duration:
- 4 h
- Remarks on result:
- other: Irritation effects on the upper respiratory tract
- Sex:
- male
- Dose descriptor:
- other: NOAEC
- Effect level:
- >= 327.7 - <= 344.1 mg/m³ air (analytical)
- Based on:
- test mat.
- Exp. duration:
- 4 h
- Remarks on result:
- other: Irritation effects on the upper respiratory tract
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
