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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
fish early-life stage toxicity
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: GLP gudeline study but only limited data available (secondary source)

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1991
Report date:
1991
Reference Type:
secondary source
Title:
European Union Risk Assessment Report, dibutyl phthalate, CAS No: 84-74-2, EINECS No: 201-557-4
Author:
EU
Year:
2004
Bibliographic source:
European Chemicals Bureau

Materials and methods

Principles of method if other than guideline:
Method: EnviroSystems Test Protocol 9102-CMA / Early life stage toxicity test with rainbow trout
GLP compliance:
yes

Test material

Constituent 1
Reference substance name:
Di-n-Butyl Phthalate (DnBP)
IUPAC Name:
Di-n-Butyl Phthalate (DnBP)
Details on test material:
- purity: 99.9 %

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
yes
Details on test solutions:
acetone

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Test type:
flow-through
Water media type:
freshwater
Limit test:
no
Total exposure duration:
99 d

Test conditions

Hardness:
180 mg/L as CaCo3
Nominal and measured concentrations:
0.14, 0.26, 0.52, 1.0, 2.0 mg/L (nominal)
0.1, 0.19, 0.40, 0.89, 1.7 mg/L (measured)

Results and discussion

Effect concentrationsopen allclose all
Duration:
99 d
Dose descriptor:
LOEC
Effect conc.:
0.19 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
length
Remarks:
and weight
Duration:
99 d
Dose descriptor:
NOEC
Effect conc.:
0.1 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
length
Remarks:
and weight

Applicant's summary and conclusion