Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
health surveillance data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: well documented and scientifically acceptable

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Unnamed
Year:
1984
Reference Type:
publication
Title:
Unnamed
Year:
1968

Materials and methods

Study type:
human medical data
Principles of method if other than guideline:
Clinical, roentgenological, and physiological study of magnetite workers
GLP compliance:
no
Remarks:
not relevant

Test material

Constituent 1
Chemical structure
Reference substance name:
Triiron tetraoxide
EC Number:
215-277-5
EC Name:
Triiron tetraoxide
Cas Number:
1317-61-9
Molecular formula:
Fe3O4
IUPAC Name:
Iron oxide
Details on test material:
Occupational exposure to iron oxide dust or fumes - inhaled particles not further specified

Method

Details on study design:
Human males, 41 magnetite miners, 16 sinters, 18 controls
Parameters: clinical examination, pulmonary function tests, x-ray of chest

Results and discussion

Results:
No consistent correlation between the clinical, radiologic, and pulmonary function findings and duration of exposure.
In miners exposed to a mixed dust a greater prevalence of respiratory, radiologic, and pulmonary function findings

Applicant's summary and conclusion

Executive summary:

In general, there was no consistent correlation between the clinical, radiologic, and

pulmonary function findings and duration of exposure