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EC number: 295-518-9
CAS number: 92062-05-0
A complex combination of hydrocarbons obtained from the vacuum distillation of the products from a thermal cracking process. It consists predominantly of hydrocarbons having carbon numbers predominantly greater than C34 and boiling above approximately 495°C (923°F).
In a dermal
sensitisation study using undiluted vaccum residue, 20 young adult male
Hartley albino guinea pigs were tested using the method of Buehler.
Normal body weight
gains were recorded for all animals during the study with the exception
of weight losses during the last 4 days of the study for three animals.
Dermal irritation ranged from very slight to well defined for erythema
and very slight for edema during the sensitisation phase. The high
sulfur levels in sample 81 -13 may have attributed to the erythema. No
dermal irritation was exhibited by either the test group or naive
control animals following the challenge application with the undiluted
test material. All 20 animals receiving the positive control material
reacted appropriately. Based on these results this test material is not
considered to be a skin sensitizer in guinea pigs by the closed patch
This study received a
Klimisch score of one and is classified as reliable without restriction
was conducted according to or similar to guideline study OECD TG 406.
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