Registration Dossier
Registration Dossier
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EC number: 204-589-7 | CAS number: 122-99-6
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
2-phenoxyethanol can be considered as hydrolytically stable with a half-life of >1 year
Key value for chemical safety assessment
Additional information
The hydrolysis of 2-phenoxyethanol (purity 99.9%) was investigated according to OECD Guideline 111 (Bayer AG 2002). The test was performed at pH 4.0, 7.0 and 9.0 in sterile buffer solutions at a temperature of 50°C. After 5 days of incubation, the hydrolytical degradation was less than 10% of the initial concentration of 0.003 mol/L for all ready buffer systems and pH values (pH 9: borax/hydrochloric acid; pH 7: potassium dihydrogen phosphate/di-sodium hydrogen phosphate; pH 4: citric acid/potassium hydroxide/sodium chloride). Therefore, 2-phenoxyethanol can be considered as hydrolytically stable with a half-life of >1 year.
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