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EC number: 203-603-9
CAS number: 108-65-6
PGME induces an adaptive hepatic response characterized by increased
S-phase DNA synthesis, likely related to cell proliferation, and
induction of MFO enzyme activity. The resultant increased metabolism of
PGME leads to an amelioration of PGME-induced sedation observed during
the first week of repeated exposure to high concentrations of this
A NOAEL of 1000 ppm was established in mice, based on slight body weight
decreases in both sexes.
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