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EC number: 203-603-9
CAS number: 108-65-6
In this skin sensitization study, groups of
male and female guinea pigs (test group – 10 male + 10 female, control
group – 5 male + 5 female) were exposed via intradermal injection to
0.1% (m/v) in corn oil, topical induction to undiluted Methyl Proxitol
Acetate and topical challenge to undiluted Methyl Proxitol Acetate. The
erythema resulting from the topical challenge was scored on a 4 point
scale immediately on removal of the challenge patches and 24 and 48
hours later. Under the conditions of the study, none of the twenty test
animals showed any positive response at either 24 and 48 hours after
removal of the challenge patches, therefore Methyl Proxitol Acetate was
not a skin sensitizer in guinea pigs
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