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EC number: 800-172-4 | CAS number: 398141-87-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Testing was conducted between 21 September 2011 and 26 September 2011.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Temp.:
- 25 °C
- Vapour pressure:
- 0.85 Pa
- Transition / decomposition:
- no
- Conclusions:
- The vapour pressure of the test item has been determined to be 8.5 x 10-1 Pa at 25ºC.
- Executive summary:
Introduction
Hazardous physico-chemical properties of the test item have been determined.
Methods employed are designed to be compatible with those specified in Commission Regulation (EC) No 440/2008 of 30 May 2008, Part A: Methods for the determination of physico-chemical properties and the current OECD Guidelines for Testing of Chemicals.
Method
The vapour pressure was determined using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using a procedure designed to be compatible with Method A4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 specified in the OECD Guidelines for Testing of Chemicals, 23 March 2006.
Conclusion
The vapour pressure of the test item has been determined to be 8.5 x 10-1 Pa at 25ºC.
Reference
Run 2
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapour Pressure (Pa) |
Log10Vp |
5 |
278.15 |
0.003595182 |
111.53 |
1.115E-07 |
0.154832214 |
-0.810138677 |
6 |
279.15 |
0.003582303 |
119.31 |
1.193E-07 |
0.165632847 |
-0.780853533 |
7 |
280.15 |
0.003569516 |
128.50 |
1.285E-07 |
0.178390922 |
-0.748627251 |
8 |
281.15 |
0.003556820 |
140.08 |
1.401E-07 |
0.194466928 |
-0.711154246 |
9 |
282.15 |
0.003544214 |
152.16 |
1.522E-07 |
0.211237063 |
-0.675229879 |
10 |
283.15 |
0.003531697 |
169.23 |
1.692E-07 |
0.234934596 |
-0.629053024 |
11 |
284.15 |
0.003519268 |
182.51 |
1.825E-07 |
0.253370639 |
-0.596243714 |
12 |
285.15 |
0.003506926 |
203.98 |
2.040E-07 |
0.283176499 |
-0.547942791 |
13 |
286.15 |
0.003494671 |
231.04 |
2.310E-07 |
0.320742712 |
-0.493843203 |
14 |
287.15 |
0.003482500 |
246.41 |
2.464E-07 |
0.342080210 |
-0.465872050 |
15 |
288.15 |
0.003470415 |
264.39 |
2.644E-07 |
0.367041056 |
-0.435285354 |
A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 2 gives the following statistical data using an unweighted least squares treatment.
Slope -3134.990
Standard deviation in slope 71.073
Intercept 10.446
Standard deviation in intercept 0.251
The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3134.990/temp(K) + 10.446
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -0.068.
Run 2 - Graph of Log10Vapour Pressure vs Reciprocal Temperature see Attachment 3 Run 2 to 5.
Run 3
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapour Pressure (Pa) |
Log10Vp |
5 |
278.15 |
0.003595182 |
105.93 |
1.059E-07 |
0.147057979 |
-0.832511406 |
6 |
279.15 |
0.003582303 |
115.02 |
1.150E-07 |
0.159677228 |
-0.796757015 |
7 |
280.15 |
0.003569516 |
123.21 |
1.232E-07 |
0.171047046 |
-0.766884421 |
8 |
281.15 |
0.003556820 |
139.48 |
1.395E-07 |
0.193633975 |
-0.713018440 |
9 |
282.15 |
0.003544214 |
154.66 |
1.547E-07 |
0.214707704 |
-0.668152373 |
10 |
283.15 |
0.003531697 |
164.84 |
1.648E-07 |
0.228840152 |
-0.640467773 |
11 |
284.15 |
0.003519268 |
180.42 |
1.804E-07 |
0.250469183 |
-0.601245700 |
12 |
285.15 |
0.003506926 |
198.99 |
1.990E-07 |
0.276249101 |
-0.558699127 |
13 |
286.15 |
0.003494671 |
219.16 |
2.192E-07 |
0.304250228 |
-0.516769087 |
14 |
287.15 |
0.003482500 |
241.42 |
2.414E-07 |
0.335152811 |
-0.474757133 |
15 |
288.15 |
0.003470415 |
265.48 |
2.655E-07 |
0.368554256 |
-0.433498570 |
A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 3 gives the following statistical data using an unweighted least squares treatment.
Slope -3212.139
Standard deviation in slope 45.011
Intercept 10.709
Standard deviation in intercept 0.159
The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3212.139/temp(K) + 10.709
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -0.064.
Run 3 - Graph of Log10Vapour Pressure vs Reciprocal Temperature see Attachment 3 Run 2 to 5.
Run 4
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapour Pressure (Pa) |
Log10Vp |
5 |
278.15 |
0.003595182 |
102.94 |
1.029E-07 |
0.142907093 |
-0.844946215 |
6 |
279.15 |
0.003582303 |
109.73 |
1.097E-07 |
0.152333353 |
-0.817205000 |
7 |
280.15 |
0.003569516 |
120.11 |
1.201E-07 |
0.166743452 |
-0.777951212 |
8 |
281.15 |
0.003556820 |
133.89 |
1.339E-07 |
0.185873622 |
-0.730782237 |
9 |
282.15 |
0.003544214 |
147.97 |
1.480E-07 |
0.205420270 |
-0.687356705 |
10 |
283.15 |
0.003531697 |
163.34 |
1.633E-07 |
0.226757767 |
-0.644437827 |
11 |
284.15 |
0.003519268 |
175.92 |
1.759E-07 |
0.244222030 |
-0.612215162 |
12 |
285.15 |
0.003506926 |
193.60 |
1.936E-07 |
0.268766400 |
-0.570625026 |
13 |
286.15 |
0.003494671 |
214.76 |
2.148E-07 |
0.298141901 |
-0.525576983 |
14 |
287.15 |
0.003482500 |
237.03 |
2.370E-07 |
0.329058367 |
-0.482727062 |
15 |
288.15 |
0.003470415 |
263.39 |
2.634E-07 |
0.365652800 |
-0.436931096 |
A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistical data using an unweighted least squares treatment.
Slope -3300.487
Standard deviation in slope 45.763
Intercept 11.010
Standard deviation in intercept 0.162
The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3300.487/temp(K) + 11.010
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -0.060.
Run 4 - Graph of Log10Vapour Pressure vs Reciprocal Temperature see Attachment 3 Run 2 to 5.
Run 5
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapour Pressure (Pa) |
Log10Vp |
5 |
278.15 |
0.003595182 |
103.74 |
1.037E-07 |
0.144017698 |
-0.841584135 |
6 |
279.15 |
0.003582303 |
113.32 |
1.133E-07 |
0.157317192 |
-0.803223813 |
7 |
280.15 |
0.003569516 |
125.70 |
1.257E-07 |
0.174503804 |
-0.758195101 |
8 |
281.15 |
0.003556820 |
134.39 |
1.344E-07 |
0.186567751 |
-0.729163425 |
9 |
282.15 |
0.003544214 |
148.57 |
1.486E-07 |
0.206253223 |
-0.685599255 |
10 |
283.15 |
0.003531697 |
163.84 |
1.638E-07 |
0.227451896 |
-0.643110439 |
11 |
284.15 |
0.003519268 |
175.13 |
1.751E-07 |
0.243125308 |
-0.614169831 |
12 |
285.15 |
0.003506926 |
190.20 |
1.902E-07 |
0.264046329 |
-0.578319866 |
13 |
286.15 |
0.003494671 |
214.36 |
2.144E-07 |
0.297586599 |
-0.526386630 |
14 |
287.15 |
0.003482500 |
230.94 |
2.309E-07 |
0.320603886 |
-0.494031217 |
15 |
288.15 |
0.003470415 |
261.69 |
2.617E-07 |
0.363292765 |
-0.439743252 |
A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 5 gives the following statistical data using an unweighted least squares treatment.
Slope -3142.998
Standard deviation in slope 53.663
Intercept 10.455
Standard deviation in intercept 0.190
The results obtained indicate the following vapour pressure relationship:
Log10(Vp (Pa)) = -3142.998/temp(K) + 10.455
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -0.087.
Run 5 - Graph of Log10Vapour Pressure vs Reciprocal Temperature see Attachment 3 Run 2 to 5.
Description of key information
The vapour pressure of the substance was determined to be 0.85 Pa; study conducted in accordance with OECD 104 and EU Method A.4; Atwal and Tremain (2011)
Key value for chemical safety assessment
- Vapour pressure:
- 0.85 Pa
- at the temperature of:
- 25 °C
Additional information
In a GLP compliant vapour pressure study conducted in accordance with standardised guidelines, the vapour pressure of the test substance was determined using the effusion method: vapour pressure balance. Under the conditions of the test, the vapour pressure of the test substance was determined to be 0.85 Pa which is considered to be a very low volatile based on EASE.
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