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Toxicity to microorganisms

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Description of key information

The 3-hour EC50 value for urea phosphate to activated sludge was >100 mg/L with a NOEC of 100 mg/L. 

Key value for chemical safety assessment

EC50 for microorganisms:
100 mg/L
EC10 or NOEC for microorganisms:
100 mg/L

Additional information

In a reliable OECD 209 guideline study, the respiration rate of the predominatly domestic sludge was determined after exposure to 100 mg/L urea phosphate for three hours. No inhibition of respiration rate of the sludge was recorded at 100 mg Urea Phosphate per litre.Therefore, the 3 -hr EC50 was determined to be >100 mg/L and the NOEC was 100 mg/L.

This was confirmed in a study with urea. The 72 hour toxicity threshold of Entosiphon sulcatum to urea was 29 mg/l, and the 16 hour toxicity threshold of urea to Pseudomonas putida was > 10000 mg/l.

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