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EC number: 200-889-7
CAS number: 75-65-0
In a reverse
gene mutation assay in bacteria using the pre-incubation method, strain
TA 102 of Salmonella typhimurium was exposed to tertiary butyl alcohol
in DMSO at concentrations of 5, 15, 50, 150, 500, 1500, and 5000
μg/plate in the presence and absence of metabolic
an independent laboratory, the study was repeated in the
plate-incorporation method using water or dried DMSO as the vehicle and
tertiary butyl alcohol concentrations of 100, 200, 500, 1000, 2500 and
5000 μg/plate. There
was no evidence of cytotoxicity in either study and the choice of
vehicle had no effect on the response. The
positive and vehicle controls induced the appropriate response.
was no statistical or dose-related increase in number of mutant colonies
over background in either study.
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