Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

The potential for tertiary butyl alcohol to cause dermal sensitization is well understood.  In a Guinea Pig Maximization Test conducted according to OECD Guidelines, a concentration of 100% tertiary butyl alcohol at challenge did not cause a sensitization reaction in female guinea pigs after prior intradermal exposures of 1% and topical exposures of 100%.

Respiratory sensitisation

Endpoint conclusion
Additional information:

No information available.

Justification for classification or non-classification

No evidence of a sensitization response was observed in a guideline dermal sensitization study conducted in guinea pigs and the subject chemical is not structurally similar to substances known to cause dermal sensitization. Based on a weight-of-the evidence assessment, tertiary butyl alcohol is not classified for dermal sensitization according to Dangerous Substances Directive 67/548/EEC and EU Classification, Labeling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.