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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09 November 2010 to 24 November 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
This study was conducted in accordance with Method A6 "Water Solubility" of Commission Regulation (EC) No 440/2008 of 30 May 2008. The study was performed in compliance with UK GLP standards (Schedule 1, Good Laboratory Practice Regulations 1999 (SI 1999/3106 as amended by SI 2004/0994).

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Reference substance name:
3-trifluoromethylaniline
IUPAC Name:
3-trifluoromethylaniline
Details on test material:
Description: 3-trifluoromethylaniline
Description: Extremely pale yellow liquid
Purity: 99.66 %
Batch Number: 101009
Date Received: 25 October 2010
Storage Conditions: Room temperature in the dark

Results and discussion

Water solubility
Water solubility:
4.68 g/L
Temp.:
20 °C
pH:
5
Remarks on result:
other: Mean pH quoted (range 4.8 - 5.2)

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
The water solubility of the test item has been determined to be 4.68 g/L at 20 degrees celsius.