Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 219-207-4 | CAS number: 2386-87-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
This study was conducted to determine the toxicity of Cycloaliphatic Epoxide Resin ERL-4221 to the green algae Selenastrum capricornutum. This study was carried out in accordance with OECD Guideline 201. The study was performed with the following nominal test concentrations: control, 5.6, 10, 18, 32, 56, 100 and 180 mg/L, mean measured exposure concentrations were 3.7, 6.6, 11, 22, 30, 27 and 110 mg/L. The results of the study are based on the mean measured concentrations.
The 72 hour EbC50was calculated to be 90 mg/L, the corresponding lowest observed effect concentration (LOEC) and no-observed effect concentration (NOEC) were calculated to be 27 and 22 mg/L. The calculated NOEC and LOEC are lower than indicated by the areas under the growth curve and therefore present a worst case result. This is due to the inclusion of the low geometric mean measured concentration for the nominal 100 mg/L concentration in the statistical analysis.
The 72 hour ErC50was observed to be >110 mg/L, the highest mean measured concentration tested. The corresponding NOEC was 30 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 110 mg/L
- EC10 or NOEC for freshwater algae:
- 30 mg/L
Additional information
This study was conducted to determine the toxicity of Cycloaliphatic Epoxide Resin ERL-4221 to the green algae Selenastrum capricornutum. This study was carried out in accordance with OECD Guideline 201. The 72 hour EbC50was calculated to be 90 mg/L, the corresponding lowest observed effect concentration (LOEC) and no-observed effect concentration (NOEC) were calculated to be 27 and 22 mg/L. The 72 hour ErC50was observed to be >110 mg/L, the highest mean measured concentration tested. The corresponding NOEC was 30 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
