Registration Dossier
Registration Dossier
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EC number: 234-576-1 | CAS number: 12012-35-0
Carcinogenicity
Administrative data
Description of key information
Long term in vivo studies with chromium metal and chromium(III) oxide do not show any evidence that chromium would be a potential carcinogen. Human exposure observations and international carcinogenicity evaluations also conclude that trivalent chromium compounds are not classifiable for carcinogenicity.
Key value for chemical safety assessment
Justification for classification or non-classification
No classification is suggested for trichromium dicarbide.
According to available data on in vivo studies with chromium metal and chromium(III) oxide, as well as human exposure data, there are no indications that chromium metal / trivalent chromium would be a carcinogen. Several extensive evaluations also conclude that chromium(III) compounds are not classifiable as carcinogens. Based on this, it can be concluded that there are no data indicating any carcinogenic potential of trichromium dicarbide.
Additional information
The available data on the carcinogenicity of insoluble chromium do not show any clear carcinogenic effects. Trivalent chromium has been evaluated for carcinogenicity by IARC, WHO, ACGIH and US EPA, and none of these evaluations have found any evidence for chromium metal or Cr(III) being a potential carcinogen.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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