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EC number: 201-553-2
CAS number: 84-69-5
with ECHA guidance, PNECs were derived for diisobutyl phthalate based on
the available ecotoxicological data with the appropriate assessment
factors applied considering the extent of the available data set.
Acute (LC50 and
EC50) data were available at three tropic levels, invertebrates, algae
and fish. The most sensitive result was for an algae. This EC50 value
was used to derive the PNEC for intermittent releases in water.
data were available at two tropic levels, algae and fish (fish data was
read across from dibutyl phthalate). The most sensitive result was for
the fish. This NOEC was used to derive the freshwater and marine water
PNEC. These results were for freshwater species, therefore a higher
assessment factor was applied to generate the marine water PNEC.
data on the toxicity of diisobutyl phthalate in sediments or soils are
available. Therefore the equilibrium partitioning method was applied to
the freshwater PNEC to obtain the PNEC for freshwater sediments and
soils, and to the marine waters PNEC to obtain the PNEC for marine
As no data were
available for the toxicity of the substance to microorganisms the PNEC
for STPs was determined from the concentration used in an inherent
biodegradability test where no inhibition of the microorganisms was
observed. This concentration was therefore considered as a NOEC. An
assessment factor (10) was applied to generate the PNEC.
Under Directive 67/548 and under GHS/CLP
diisobutyl phthalate has not been currently been classified as hazardous
to the environment.
Given the available data in this assessment
(lowest acute effect concentration 0.56mg/l and a log Kow of 4.11),
under GHS/CLP the substance would be classified as both Acute and
Chronic Category 1. Under Directive 67/548 the substance would be
classifiedR50/R53 Very toxic to aquatic organisms, may
cause long-term adverse effects in the aquatic environmentand
would have the symbol‘N: Dangerous for the environment’.
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