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EC number: 278-780-9
CAS number: 77881-13-1
No mortalities occurred. Moreover, no
compound-related findings were observed in body weight gain or autopsy. Main
clinical findings were spastic gait and ruffled fur which were observed on
the first day after application in all dose groups. From day 2 onwards all
animals were without findings.
In an orientating toxicity study the single
oral administration of the test substance (ZK 74.804) to male rats at
doses of 0.25, 0.5, 1.0, 2.0, 3.5 and 5 g/kg was tolerated without any
mortality or compound-related macroscopic pathological signs. Main
clinical findings were spastic gait and ruffled fur which were observed
on the first day after application in all dose groups. From day 2
onwards all animals were without findings.
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