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EC number: 212-985-6 | CAS number: 901-44-0
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from September 28, 2001 to June 26, 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: In the study report there are no relevant deviations from OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2,2'-isopropylidenebis(p-phenyleneoxy)diethanol
- EC Number:
- 212-985-6
- EC Name:
- 2,2'-isopropylidenebis(p-phenyleneoxy)diethanol
- Cas Number:
- 901-44-0
- Molecular formula:
- C19H24O4
- IUPAC Name:
- 2,2'-isopropylidenebis(p-phenyleneoxy)diethanol
- Reference substance name:
- 2-[4-[2-[4-(2-hydroxyethoxy)phenyl]propan-2-yl]phenoxy]ethanol
- IUPAC Name:
- 2-[4-[2-[4-(2-hydroxyethoxy)phenyl]propan-2-yl]phenoxy]ethanol
- Reference substance name:
- O(CCO)c1ccc(cc1)C(c1ccc(OCCO)cc1)(C)C
- IUPAC Name:
- O(CCO)c1ccc(cc1)C(c1ccc(OCCO)cc1)(C)C
- Details on test material:
- - Name of test material (as cited in study report): 2,2'-[(propane-2,2-diyl)bis(p-phenyleneoxy)]diethanol
- Molecular formula (if other than submission substance): C19-H24-O4
- Molecular weight (if other than submission substance): 316.4 g/mol
- Smiles notation (if other than submission substance): O(CCO)c1ccc(cc1)C(c1ccc(OCCO)cc1)(C)C
- InChl (if other than submission substance): InChI=1/C19H24O4/c1-19(2,15-3-7-17(8-4-15)22-13-11-20)16-5-9-18(10-6-16)23-14-12-21/h3-10,20-21H,11-14H2,1-2H3
- Other: Physical state: White powder
Constituent 1
Constituent 2
Constituent 3
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
PHYSICO-CHEMICAL PROPERTIES
- Melting point: 105℃
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- Using active sludge was Standard active sludge in Japan, which was prepared according to OECD test guideline 301C.
- Concentration of Activated Sludge: 30mg/L - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimationopen allclose all
- Parameter followed for biodegradation estimation:
- other: BOD
- Parameter followed for biodegradation estimation:
- DOC removal
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Remarks:
- HPLC
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradationopen allclose all
- Parameter:
- other: BOD
- Value:
- 1
- St. dev.:
- 0.6
- Sampling time:
- 28 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 25
- St. dev.:
- 2
- Sampling time:
- 28 d
- Remarks on result:
- other: HPLC
- Details on results:
- As the test sample was few soluble in water, the ultimate biodegradation could not estimated by DOC removal.
BOD5 / COD results
- Results with reference substance:
- The degradation of the positive control substance aniline reached the level of 57% of degradation on Day 7.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The substance is not readily biodegradable.
- Executive summary:
The biodegradation rate from BOD was 1 percent, and the biodegradation rate calculated from the concentration of remaining test substance, by means of HPLC, was 25 percent.
Tested substance degrades to another chemicals by active sludge, however the substances formed were not estimated as readily biodegradable.
Therefore the test substance was not readily biodegradable.
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