Registration Dossier
Registration Dossier
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EC number: 200-268-0 | CAS number: 56-35-9
Neurotoxicity
Administrative data
Description of key information
The available data were both in the form of reviews, however both concurred that TBTO does not appear to possess neurotoxic effects.
Key value for chemical safety assessment
Additional information
Neither of the available studies, Schweinfurth H (1986) and Schweinfurth H et al (1986) were sufficient for assessment as both were reviews of literature and studies performed by the same laboratory.
Justification for classification or non-classification
The substance is included in the group of substances "tributyltin compounds" which is itself included in Annex VI to Regulation (EC) No 1272/2008 with Index Number 050-008-00-3. The entry has been assigned the hazard classification of STOT RE 1 H372 (Causes damage to organs (state all organs affected, if known) through prolonged or repeated exposure (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard)).
Available information indicates very little effect on behavioural effects or changes to the central nervous system and spinal cord specifically.
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