Registration Dossier
Registration Dossier
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EC number: 244-005-8 | CAS number: 20748-72-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to fish.
Key value for chemical safety assessment
Additional information
(2-hydroxyethyl)ammonium nitrate is completely soluble in water and dissociates to (2 -hydroxyethyl)ammonium and nitrate ions.
Since no studies on the aquatic toxicity of the substance (2 -hydroxyethyl)ammonium nitrate are available, study reports and published literature about the toxic effects of its dissociation products have been consulted alternatively.The effect of monoethanolamine (CAS 141-43-5) on several fish species including fathead minnow (Pimephales promelas), goldfish (Carassius auratus), common carp (Cyprinus carpio), golden orfe (Leuciscus idus) and ricefish (Oryzias latipes) has been investigated by several scientists [Huels AG 1997, Geiger et al. 1990, Bridie et al. 1973, Juhnke and Luedemann 1978 and NITE 1996].
The LC50 values for 96-hour exposure range from 170 mg/l for goldfish to 2070 mg/l for fathead minnow. Studies in which the pH was measured indicate that the test material increased pH to approximately 10.1 – 10.2 in some of the studies. Studies performed in goldfish show that the LC50 value of monoethanolamine increases dramatically if the pH is neutralized, suggesting that the studies with lower LC50 values may have been influenced by high pH.
Trama (1954) derived an LC50 of 12000 mg/L sodium nitrate (equals 8753 mg/L nitrate) from non-GLP fish tests with Lepomis macrochirus. These results are supported by studies conducted with several different fish species (e.g.Gambusia affinis, Oncorhynchus tschawytscha, Salmo gairdneri) that resulted in LC50 values between 4400 - 6000 mg/L nitrate (Wallen et al., 1957 and Westin, 1974).
Thus, neither 2-aminoethanol nor nitrate is considered as harmful to fish.
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