Registration Dossier
Registration Dossier
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EC number: 203-729-4 | CAS number: 110-02-1
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: 2a: Data from international report and study was performed according to OECD guideline without detail documentation.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- SIDS INITIAL ASSESSMENT PROFILE
- Author:
- OECD
- Year:
- 2 011
- Bibliographic source:
- UNEP publications
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- No further details
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Thiophene
- EC Number:
- 203-729-4
- EC Name:
- Thiophene
- Cas Number:
- 110-02-1
- Molecular formula:
- C4H4S
- IUPAC Name:
- thiophene
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Duration of exposure:
- 6 h
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 4 525 ppm
- Based on:
- not specified
- Exp. duration:
- 6 h
- Remarks on result:
- other: = 15.6 mg/l
Applicant's summary and conclusion
- Conclusions:
- The inhalation LC50 was reported to be 4525 ppm (15.6 mg/L) for a 6 h exposure in rats.
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