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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

Waiving of experimental study. EC50 for algae was calculated to be ca. 26857 mg/L.

Key value for chemical safety assessment

Additional information

Data from a higher trophic level (fish and invertebrates) are available which lead to the conclusion that aquatic toxicity does not occur. In accordance with Annex XI No. 1.2 an experimental study is not conducted as there is sufficient weight of evidence from several independent sources of information leading to the assumption/conclusion that the substance does not cause aquatic toxicity to algae.

EC50 for algae was calculated to be ca. 26857 mg/L. Considering the fact that calculation models for aquatic toxicity to algae usually produce values which are conservative to unrealistic conservative, even the estimated high EC50 might not reflect actual toxicity to algae by L-arginine-HCl. Higher EC50 might be possible.

L-arginine-HCl is present as L-arginine under physiological conditions. L-arginine a is a naturally occuring amino acid which is omnipresent bin nature. It is a basic metabolit and building block of all living organisms and cells and is also a nutrient for algae.Thus significant toxicity to algae by L-arginine-HCl can be excluded.